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The use of one drug can lead to long and short term side-effects. For example, you can read all about how ketamine works and the effects it has on the body and the brain in another resource in our collection.

One drug may be easier to predict in terms of side effects, but combining two or more drugs can be much more dangerous based on how the substances combine together in the body, and how they have physical and psychological reactions.

In this resource we have written about mixing ketamine (sometimes known as Kit Kat) with MDMA, but we have written additional articles about different combinations if you want to learn more:


Should you mix ketamine and MDMA?

Just like alcohol, MDMA (known to most people as ecstasy) can be frequently found in clubbing environments and festivals, so it may be tempting to top up the use of ecstasy with some ketamine later on in the night (or early morning).

Yet both drugs operate differently in the body. Remember that ketamine is a dissociative anaesthetic and a sedative, but MDMA is a stimulant drug that is known for its euphoric and mildly hallucinogenic effects.

Mixing drugs can be dangerous, both because of side effects, but also the increased risk of having accidents or situations that you would usually avoid.


If you do find yourself in the situation where MDMA (ecstasy) and ketamine have been used together, there are some key things to be aware of for safety.

Tell someone

When you have been clubbing and taken both ecstasy and K (ketamine), let a sober friend know, and stay with the group you came with. If you feel overwhelmed in a venue, call a friend to come and get you, and stay with them overnight.

Be aware of side effects

The side effects from this combination of drugs is not widely reported, but can differ depending on the dosages taken. If you feel unwell at any point, seek immediate medical attention from the emergency services.

If your friend or someone you have met has become ill after taking MDMA and ketamine, take care of them until help arrives.

You will need time to recover

Using a stimulant with a sedative will not make it easy to get up for work in the morning. Consider this before you choose to combine any drugs in the future.


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Need to speak to us?

Call the emergency services on 999 (UK only) if you are concerned about an overdose or bad reaction from mixing any combination of drugs.

Delamere is here if you want to stop taking ketamine and/or MDMA with the support of our private rehabilitation clinic. We can help you on the road to recovery, giving you the tools to get to grips with your addiction or reliance on certain substances.

Speak to our admissions team by giving us a call today, or you can contact us online through our web form, live chat function, or by email.

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